Abstract
In 2012, we learned that functional thyroid tissue can be generated in vitro, and that thyroid hormones stimulate autophagy. Patients with defects in TRα have been identified, and di-iodothyropropionic acid has been shown to ameliorate MCT8 deficiency. Finally, we found that gene expression profiling can identify benign thyroid nodules.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Autophagy
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Humans
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Hypothyroidism / drug therapy
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Hypothyroidism / genetics
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Hypothyroidism / therapy*
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Monocarboxylic Acid Transporters / genetics
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Monocarboxylic Acid Transporters / metabolism
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Receptors, Thyroid Hormone / genetics
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Receptors, Thyroid Hormone / metabolism
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Symporters
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Thyroid Gland / cytology*
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Thyroid Gland / metabolism*
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Thyroid Hormones / metabolism*
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Thyroid Neoplasms / diagnosis
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Thyroid Neoplasms / surgery
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Thyroid Neoplasms / therapy*
Substances
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Monocarboxylic Acid Transporters
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Receptors, Thyroid Hormone
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SLC16A2 protein, human
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Symporters
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Thyroid Hormones