Chondrosarcoma in childhood: the radiologic and clinical conundrum

J Radiol Case Rep. 2012 Dec;6(12):32-42. doi: 10.3941/jrcr.v6i12.1241. Epub 2012 Dec 1.

Abstract

Less than 10% of chondrosarcomas occur in children. In addition, as little as 0.5% of low-grade chondrosarcomas arise secondarily from benign chondroid lesions. The presence of focal pain is often used to crudely distinguish a chondrosarcoma (which is usually managed with wide surgical excision), from a benign chondroid lesion (which can be followed by clinical exams and imaging surveillance). Given the difficulty of localizing pain in the pediatric population, initial radiology findings and short-interval follow-up, both imaging and clinical, are critical to accurately differentiate a chondrosarcoma from a benign chondroid lesion. To our knowledge, no case in the literature discusses a chondrosarcoma possibly arising secondarily from an enchondroma in a pediatric patient. We present a clinicopathologic and radiology review of conventional chondrosarcomas. We also attempt to further the understanding of how to manage a chondroid lesion in the pediatric patient with only vague or bilateral complaints of pain.

Keywords: bone tumor; chondrosarcoma; pediatric; pediatric chondrosarcoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Bone Cysts / diagnosis
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / pathology
  • Bone Neoplasms / surgery
  • Child
  • Chondroma / diagnosis
  • Chondrosarcoma / diagnosis*
  • Chondrosarcoma / diagnostic imaging
  • Chondrosarcoma / pathology
  • Chondrosarcoma / surgery
  • Contrast Media
  • Diagnosis, Differential
  • Femur / diagnostic imaging*
  • Femur / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Radiography
  • Time Factors
  • Treatment Outcome

Substances

  • Contrast Media