Automated EEG inter-burst interval detection in neonates with mild to moderate postasphyxial encephalopathy

Annu Int Conf IEEE Eng Med Biol Soc. 2012:2012:17-20. doi: 10.1109/EMBC.2012.6345860.

Abstract

EEG inter-burst interval (IBI) and its evolution is a robust parameter for grading hypoxic encephalopathy and prognostication in newborns with perinatal asphyxia. We present a reliable algorithm for the automatic detection of IBIs. This automated approach is based on adaptive segmentation of EEG, classification of segments and use of temporal profiles to describe the global distribution of EEG activity. A pediatric neurologist has blindly scored data from 8 newborns with perinatal postasphyxial encephalopathy varying from mild to severe. 15 minutes of EEG have been scored per patient, thus totaling 2 hours of EEG that was used for validation. The algorithm shows good detection accuracy and provides insight into challenging cases that are difficult to detect.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Asphyxia Neonatorum* / complications
  • Asphyxia Neonatorum* / diagnosis
  • Asphyxia Neonatorum* / physiopathology
  • Brain Diseases* / diagnosis
  • Brain Diseases* / etiology
  • Brain Diseases* / physiopathology
  • Electroencephalography / methods*
  • Electronic Data Processing / methods*
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Signal Processing, Computer-Assisted*