Cranberry containing products can protect against recurrent UTIs. The duration of treatment for uncomplicated pyelonephritis can be safely shortened to 7 days when using ciprofloxacin. Early surgical treatment for infective endocarditis in patients with large vegetations (> 10 mm) and valve dysfunction should be considered, even in the absence of urgent indications for surgery. Enterobacteriaceae with ESBL are less transmitted in hospital than in households. Tattoo ink-related mycobacterial infections are increasingly reported, even in Western Switzerland. Differentiating acute bacterial from viral rhinosinusitis on clinical criteria remains difficult. Antibiotic and non-antibiotic prevention of acute exacerbations of COPD is still a hot topic, we propose to discuss here.