Histological diagnosis of follicular lymphoma by biopsy of small intestinal normal mucosa

Dig Endosc. 2013 Sep;25(5):544-6. doi: 10.1111/j.1443-1661.2012.01386.x. Epub 2012 Oct 22.

Abstract

Due to advances in double-balloon endoscopy, various types of malignant lymphoma of the small intestine have been observed at very early stages. We report here that after remission of diffuse large B-cell lymphoma, follicular lymphoma recurred in the mucosa of the small intestine. Furthermore, these lesions were diagnosed by biopsy from normal mucosa as diminutive erosions and reddish looking. If a small intestinal lesion is suspected of being a malignant lymphoma, a double-balloon endoscopy should be carried out, and a biopsy should be taken and inspected.

Keywords: double-balloon endoscopy; endoscopically normal mucosa; follicular lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Double-Balloon Enteroscopy / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Ileal Neoplasms / diagnosis*
  • Ileal Neoplasms / pathology
  • Immunohistochemistry
  • Intestinal Mucosa / pathology*
  • Lymphoma, Follicular / diagnosis
  • Lymphoma, Follicular / pathology*
  • Lymphoma, Follicular / therapy
  • Lymphoma, Large B-Cell, Diffuse / diagnosis
  • Lymphoma, Large B-Cell, Diffuse / pathology*
  • Lymphoma, Large B-Cell, Diffuse / therapy
  • Melena / diagnosis
  • Melena / etiology
  • Middle Aged
  • Recurrence
  • Treatment Outcome