Synthesis of novel aryl and heteroaryl acyl sulfonimidamides via Pd-catalyzed carbonylation using a nongaseous precursor

Org Lett. 2013 Mar 1;15(5):1056-9. doi: 10.1021/ol400049m. Epub 2013 Feb 8.

Abstract

Hitherto unexplored aryl and heteroaryl acyl sulfonimidamides have been prepared through the development of a new Pd-catalyzed carbonylation protocol. This novel methodology, employing sulfonimidamides as nucleophiles and CO gas ex situ released from solid Mo(CO)6 in a sealed two-chamber system, yields a wide range of carbamate protected acyl sulfonimidamides in good to excellent yields.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Molecular Structure
  • Palladium / chemistry*
  • Sulfur Compounds / chemical synthesis*
  • Sulfur Compounds / chemistry*

Substances

  • Sulfur Compounds
  • Palladium