Can the edge-to-edge technique provide durable results when used to rescue patients with suboptimal conventional mitral repair?

Eur J Cardiothorac Surg. 2013 Jun;43(6):e173-9. doi: 10.1093/ejcts/ezt056. Epub 2013 Feb 13.

Abstract

Objectives: The 'edge-to-edge' technique (EE) can be used as a bailout procedure in case of a suboptimal result of conventional mitral valve (MV) repair. The aim of this study was to assess the long-term outcomes of this technique used as a rescue procedure.

Methods: From 1998 to 2011, of 3861 patients submitted to conventional MV repair for pure mitral regurgitation (MR), 43 (1.1%) underwent a rescue edge-to-edge repair for significant residual MR at the intraoperative hydrodynamic test or at the intraoperative transoesophageal echocardiography. Residual MR was due to residual prolapse in 30 (69.7%) patients, systolic anterior motion in 12 (27.9%) and post-endocarditis leaflet erosion in 1 (2.3%). According to the location of the regurgitant jet, the edge-to-edge suture was performed centrally (60.5%) or in correspondence with the anterior or posterior commissure (39.5%). The original repair was left in place.

Results: There were no hospital deaths. Additional cross-clamp time was 15.2 ± 5.6 min. At hospital discharge, all patients showed no or mild MR and no mitral stenosis. Clinical and echocardiographic follow-up was 97.6% complete (median length 5.7 years, up to 14.6 years). At 10 years, actuarial survival was 89 ± 7.4% and freedom from cardiac death 100%. Freedom from reoperation and freedom from MR ≥ 3+ at 10 years were both 96.9 ± 2.9%. At the last echocardiogram, MR was absent or mild in 37 patients (88%), moderate in 4 (9.5%) and severe in 1 (2.4%). No predictors for recurrence of MR ≥ 2+ were identified. The mean MV area and gradient were 2.8 ± 0.6 cm(2) and 2.7 ± 0.9 mmHg. NYHA I-II was documented in all cases.

Conclusions: A 'rescue' EE can be a rapid and effective option in case of suboptimal result of 'conventional' MV repair. Long-term durability of the repair is not compromised.

Keywords: Edge-to-edge technique; Mitral regurgitation; Mitral valve repair.

MeSH terms

  • Aged
  • Analysis of Variance
  • Echocardiography, Doppler
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve / surgery*
  • Mitral Valve Annuloplasty / methods*
  • Mitral Valve Annuloplasty / mortality
  • Mitral Valve Annuloplasty / statistics & numerical data
  • Mitral Valve Insufficiency / surgery*
  • Recurrence
  • Retrospective Studies
  • Statistics, Nonparametric
  • Survival Analysis
  • Treatment Outcome