The Arabidopsis tandem CCCH zinc finger proteins AtTZF4, 5 and 6 are involved in light-, abscisic acid- and gibberellic acid-mediated regulation of seed germination

Plant Cell Environ. 2013 Aug;36(8):1507-19. doi: 10.1111/pce.12084. Epub 2013 Mar 14.

Abstract

Tandem CCCH zinc finger proteins (TZFs) are post-transcriptional regulators of gene expression in animals and yeast. Genetic studies indicate that plant TZFs are involved in hormone-mediated developmental and environmental responses. We have demonstrated previously that Arabidopsis AtTZF1 can localize to processing bodies (PBs) and stress granules (SGs), and affects abscisic acid (ABA)- and gibberellic acid (GA)-mediated growth, stress and gene expression responses. Here we show that AtTZF4, 5 and 6 are specifically expressed in seeds. Consistent with the observation that their expression levels decline during seed imbibition, AtTZF4, 5 and 6 are up-regulated by ABA and down-regulated by GA. Mutant analyses indicate that AtTZF4, 5 and 6 act as positive regulators for ABA- and negative regulators for light- and GA-mediated seed germination responses. Results of gene expression analysis indicate that AtTZF4, 5 and 6 affect seed germination by controlling genes critical for ABA and GA response. Furthermore, AtTZF4, 5 and 6 can co-localize with both PB and SG markers in Arabidopsis cells. Specifically, AtTZF6 can be assembled into PBs and SGs in embryos with the induction of stress hormone methyl jasmonate under the control of native AtTZF6 promoter.

Keywords: ABA; GA; PBs; SGs; TZF; processing bodies; stress granules.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abscisic Acid / pharmacology
  • Arabidopsis / cytology
  • Arabidopsis / drug effects
  • Arabidopsis / genetics
  • Arabidopsis / physiology*
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism*
  • Cytoplasmic Granules
  • Flowers / cytology
  • Flowers / drug effects
  • Flowers / genetics
  • Flowers / physiology
  • Gene Expression Regulation, Plant*
  • Genes, Reporter
  • Germination
  • Gibberellins / pharmacology
  • Models, Biological
  • Mutation
  • Organ Specificity
  • Plant Dormancy
  • Plant Growth Regulators / pharmacology*
  • Plant Leaves / cytology
  • Plant Leaves / drug effects
  • Plant Leaves / genetics
  • Plant Leaves / physiology
  • Plants, Genetically Modified
  • Seedlings / cytology
  • Seedlings / drug effects
  • Seedlings / genetics
  • Seedlings / physiology
  • Seeds / cytology
  • Seeds / drug effects
  • Seeds / genetics
  • Seeds / physiology*
  • Transcription Factors / genetics
  • Transcription Factors / metabolism
  • Zinc Fingers

Substances

  • Arabidopsis Proteins
  • Gibberellins
  • Plant Growth Regulators
  • TZF4 protein, Arabidopsis
  • TZF5 protein, Arabidopsis
  • TZF6 protein, Arabidopsis
  • Transcription Factors
  • Abscisic Acid
  • gibberellic acid