Confounding by repetitive elements and CpG islands does not explain the association between hypomethylation and genomic instability
PLoS Genet
.
2013;9(2):e1003333.
doi: 10.1371/journal.pgen.1003333.
Epub 2013 Feb 28.
Authors
R Alan Harris
1
,
Chad Shaw
,
Jian Li
,
Sau Wai Cheung
,
Cristian Coarfa
,
Mira Jeong
,
Margaret A Goodell
,
Lisa D White
,
Ankita Patel
,
Sung-Hae Kang
,
A Craig Chinault
,
Tomasz Gambin
,
Anna Gambin
,
James R Lupski
,
Aleksandar Milosavljevic
Affiliation
1
Bioinformatics Research Laboratory, Epigenome Center, Baylor College of Medicine, Houston, Texas, USA.
PMID:
23468659
PMCID:
PMC3585018
DOI:
10.1371/journal.pgen.1003333
No abstract available
Publication types
Research Support, N.I.H., Extramural
MeSH terms
CpG Islands / genetics
DNA Methylation*
Genome, Human
Genomic Instability*
Humans
Interspersed Repetitive Sequences / genetics*
Mutation Rate
Grants and funding
P30 CA125123/CA/NCI NIH HHS/United States
R01 DK092883/DK/NIDDK NIH HHS/United States
U01 DA025956/DA/NIDA NIH HHS/United States