Antenatal and intrapartum risk factors for cerebral palsy in term and near-term newborns

Arch Iran Med. 2013 Apr;16(4):213-6.

Abstract

Background: Cerebral palsy (CP) is one of the main disabilities in term-born infants. This study attempts to investigate the maternal and neonatal factors associated with CP.

Methods: This case-control study consisted of singleton term and near-term (36 or more weeks of gestation) newborns in Tehran health-care centers and was conducted over a 24-month period. Logistic regression analysis analyzed the data with SPSS 16.0.

Results: During the study period there were 53 infants in the case group and 106 in the control group. The main factors associated with CP were perinatal asphyxia [odds ratio (OR): 97.72; CI: 21.2-450.07], maternal age >35 years (OR: 20.89; CI: 1.05-412.62), and high risk pregnancy (OR: 0.2; CI: 0.04-0.932).

Conclusions: Several maternal, antenatal and intrapartum factors increase the risk for CP. Identifying and avoiding risks for CP may lead to lower infant neurologic morbidity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Asphyxia Neonatorum / complications
  • Birth Weight
  • Case-Control Studies
  • Cerebral Palsy / etiology*
  • Female
  • Humans
  • Infant, Newborn
  • Maternal Age
  • Pregnancy
  • Risk Factors