Validation of the measurement of intra-abdominal fat between ultrasound and CT scan in women with obesity and infertility

Obesity (Silver Spring). 2014 Feb;22(2):537-44. doi: 10.1002/oby.20452. Epub 2013 Jun 13.

Abstract

Objective: To compare the means and changes over time of intra-abdominal fat (IAF) and subcutaneous abdominal fat (SAF) measured by abdominal ultrasound (US) and computerized tomography (CT).

Design and methods: Prospective cohort study of 53 women with obesity and infertility undergoing a lifestyle program.

Results: The Pearson's correlation between IAF measurement by US compared to CT was good at baseline, month 3 and 6 (all r ≥ 0.72). The correlation of SAF measurement by US compared to CT was reasonable at baseline (r = 0.54; 95%CI 0.30-0.78) and weak at month 3 and 6 (all r ≤ 0.39). The correlation between the changes in IAF over 3 and 6 months by US compared to CT was reasonable and significant respectively (all r > 0.48). US could not measure the changes of SAF over time. The Bland-Altman plot showed good agreement between US and CT for IAF measurements (-1.1 [95%CI -3.9-1.6] cm lower mean in US) at baseline. For changes of IAF over time, mean estimates were in agreement.

Conclusion: In women with obesity and infertility, measuring IAF by US is in good agreement with the CT scan methodology but the measurement of SAF by US is unreliable.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adiposity*
  • Adult
  • Body Mass Index
  • Cohort Studies
  • Combined Modality Therapy
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infertility, Female / complications*
  • Infertility, Female / therapy
  • Intra-Abdominal Fat / diagnostic imaging*
  • Life Style
  • Obesity / complications
  • Obesity / diagnostic imaging*
  • Obesity / therapy
  • Obesity, Abdominal / complications
  • Obesity, Abdominal / diagnostic imaging
  • Obesity, Abdominal / therapy
  • Prospective Studies
  • Reproducibility of Results
  • Subcutaneous Fat, Abdominal / diagnostic imaging
  • Tomography, X-Ray Computed
  • Ultrasonography
  • Waist Circumference
  • Weight Loss