Supplementation of fibrinogen concentrate in children with severe acquired hypofibrinogenaemia during chemotherapy for acute lymphoblastic leukaemia: our experience

Blood Transfus. 2014 Jan;12 Suppl 1(Suppl 1):s156-7. doi: 10.2450/2013.0228-12. Epub 2013 Mar 5.

Authors

Paola Giordano¹, Matteo Luciani², Massimo Grassi¹, Francesco De Leonardis¹, Valentina Coletti², Nicola Santoro¹

Affiliations

¹ Division of Paediatric Haematology-Oncology, University of Bari, Bari, Italy.
² Division of Paediatric Haematology, Bambino Gesù Children's and Research Hospital, Rome, Italy.

No abstract available

Publication types

Letter

MeSH terms

Adolescent
Afibrinogenemia / drug therapy*
Afibrinogenemia / etiology
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Asparaginase / administration & dosage
Asparaginase / adverse effects*
Asparaginase / antagonists & inhibitors
Child
Child, Preschool
Female
Fibrinogen / therapeutic use*
Hemorrhage / prevention & control
Humans
Male
Plasma
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / blood
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / blood
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Thrombosis / prevention & control

Substances

Fibrinogen
Asparaginase