Bisphosphonate-associated osteonecrosis of the auditory canal

Br J Oral Maxillofac Surg. 2013 Dec;51(8):e285-7. doi: 10.1016/j.bjoms.2013.02.013. Epub 2013 Mar 22.

Abstract

Only rare cases of osteonecrosis of the auditory canal associated with bisphosphonates, have been published. Our results confirm that similar reports can also be encountered in databases of adverse drug reactions.

Keywords: Adverse effect; Auditory canal; Bisphosphonate; Bisphosphonate therapy; Bone exposure; External ear canal; Medicine; Osteonecrosis; Pathology.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alendronate / adverse effects
  • Bisphosphonate-Associated Osteonecrosis of the Jaw / diagnosis*
  • Bone Density Conservation Agents / adverse effects
  • Ear Canal / pathology*
  • Ear Diseases / diagnosis*
  • Female
  • Follow-Up Studies
  • Humans
  • Osteoporosis / drug therapy
  • Otitis Externa / diagnosis

Substances

  • Bone Density Conservation Agents
  • Alendronate