Significant expansion of the fluorescent protein chromophore through the genetic incorporation of a metal-chelating unnatural amino acid

Angew Chem Int Ed Engl. 2013 Apr 26;52(18):4805-9. doi: 10.1002/anie.201301307. Epub 2013 Mar 28.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alanine / chemistry
  • Alanine / metabolism
  • Amino Acids / chemistry*
  • Amino Acids / metabolism
  • Catalytic Domain
  • Chelating Agents / chemistry*
  • Citrobacter freundii / enzymology
  • Fluorescence Resonance Energy Transfer
  • Hydroxyquinolines / chemistry
  • Luminescent Proteins / chemistry*
  • Luminescent Proteins / metabolism
  • Metals / chemistry
  • Mutation
  • Spectrophotometry, Ultraviolet
  • Tyrosine Phenol-Lyase / chemistry
  • Tyrosine Phenol-Lyase / genetics
  • Tyrosine Phenol-Lyase / metabolism

Substances

  • Amino Acids
  • Chelating Agents
  • Hydroxyquinolines
  • Luminescent Proteins
  • Metals
  • Tyrosine Phenol-Lyase
  • Alanine