Genomic approaches to chronic lymphocytic leukemia

Hematol Oncol Clin North Am. 2013 Apr;27(2):157-71. doi: 10.1016/j.hoc.2013.01.001.

Abstract

This article discusses recent advances in genomic approaches used to understand chronic lymphocytic leukemia. Tools for analyzing DNA-level lesions are described, data obtained from these various platforms summarized, and the clinical relevance of these findings discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Comparative Genomic Hybridization
  • Genetic Linkage
  • Genome-Wide Association Study
  • Genomics* / methods
  • Germ Cells
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / diagnosis
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / mortality
  • Polymorphism, Single Nucleotide
  • Prognosis