Failure to control hyperglycemia in noncritically ill diabetes patients despite standard glycemic management in a hospital setting

J Diabetes Sci Technol. 2013 Mar 1;7(2):402-9. doi: 10.1177/193229681300700217.

Abstract

Background: Successful control of hyperglycemia has been shown to improve outcomes for diabetes patients in a clinical setting. We assessed the quality of physician-based glycemic management in two general wards, considering the most recent recommendations for glycemic control for noncritically ill patients (<140 mg/dl for premeal glucose).

Methods: Quality of glycemic management of 50 patients in two wards (endocrinology, cardiology) was assessed retrospectively by analyzing blood glucose (BG) levels, the glycemic management effort, and the online questionnaire.

Results: Glycemic control was clearly above the recommended target (mean BG levels: endocrinology: 175 ± 62 mg/dl; cardiology: 186 ± 68 mg/dl). When comparing the first half with the second half of the hospital stay, we found no difference in glycemic control (endocrinology: 168 ± 32 vs 164 ± 42 mg/dl, P = .67; cardiology: 174 ± 36 mg/dl vs 170 ± 42 mg/dl, P =.51) and in insulin dose (endocrinology: 15 ± 14 IU vs 15 ± 13 IU per day, P = .87; cardiology: 27 ± 17 IU vs 27 ± 18 IU per day, P = .92), despite frequent BG measurements (endocrinology: 2.7 per day; cardiology: 3.2 per day). A lack of clearly defined BG targets was indicated in the questionnaire.

Conclusion: The recommended BG target range was not achieved in both wards. Analysis of routine glycemic management demonstrated considerable glycemic management effort, but also a lack of translation into adequate insulin therapy. Implementation of corrective measures, such as structured treatment protocols, is essential.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Glucose / analysis
  • Cardiology Service, Hospital / statistics & numerical data
  • Diabetes Mellitus / blood*
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / therapy*
  • Endocrinology / statistics & numerical data
  • Female
  • Hospitals / statistics & numerical data
  • Humans
  • Hyperglycemia / blood
  • Hyperglycemia / epidemiology
  • Hyperglycemia / therapy*
  • Male
  • Middle Aged
  • Monitoring, Physiologic / methods
  • Monitoring, Physiologic / standards*
  • Quality of Health Care / statistics & numerical data
  • Retrospective Studies
  • Standard of Care*
  • Treatment Failure

Substances

  • Blood Glucose