Investigation on infrared laser desorption of solid matrix using scanning electron microscope and fast photography

Microsc Res Tech. 2013 Jul;76(7):744-50. doi: 10.1002/jemt.22225. Epub 2013 May 7.

Abstract

Infrared light from a pulsed optical parametric oscillator laser system was used to irradiate succinic acid (SA), a usual solid matrix used in matrix-assisted laser desorption ionization, under vacuum. Ablated SA particles were trapped using a silica plate mounted 3.0 mm above and parallel to the sample surface. The morphology and particle size of ablated particles at different laser fluences were investigated using a scanning electron microscope (SEM). The dynamics of plume propagation for SA desorption process was studied with fast photography at atmospheric pressure. Plume expanding at 1.12 J/cm(2) laser fluence was recorded using a high-speed CMOS camera and corresponding propagation distance was measured. The solid matrix desorption was driven by phase explosion according to plume model fitting, which was consistent with the results of SEM.

Publication types

  • Research Support, Non-U.S. Gov't