Phosphate induced crystal acute kidney injury - an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature

Int J Nephrol Renovasc Dis. 2013 Mar 16:6:61-4. doi: 10.2147/IJNRD.S41428. Print 2013.

Abstract

Acute phosphate nephropathy or nephrocalcinosis is a tubulointerstitial nephropathy characterized by tubular calcium phosphate deposition - crystal nephropathy - and slowly progressive renal insufficiency during or following treatment with preparations containing sodium phosphate. We report a patient who developed nephrocalcinosis (crystal induced acute kidney injury) following the administration of a combination of oral and rectal sodium phosphate for treatment of postoperative constipation. A timely renal replacement therapy procedure may reverse the process of crystallization and the irreversible slope towards chronic dialysis.

Keywords: CRRT; acute phosphate nephropathy; crystal induced nephropathy; dialysis; hemofiltration; hyperphosphatemie; worse prognosis.

Publication types

  • Case Reports