Neuroscience. Illuminating the neural circuitry of compulsive behaviors

Science. 2013 Jun 7;340(6137):1174-5. doi: 10.1126/science.1239652.

Abstract

In this issue, two ground-breaking reports describe the use of optogenetics to control a brain circuit that drives repetitive behavior, opening up new possibilities for the treatment of compulsive disorders.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Compulsive Behavior / therapy*
  • Corpus Striatum / physiopathology*
  • Frontal Lobe / physiopathology*
  • Male
  • Nerve Tissue Proteins / genetics*
  • Obsessive-Compulsive Disorder / physiopathology*
  • Obsessive-Compulsive Disorder / psychology*
  • Optogenetics / methods*
  • Thalamus / physiopathology*

Substances

  • Nerve Tissue Proteins
  • Sapap3 protein, mouse