A phylogenetic analysis of the phylum Fibrobacteres

Syst Appl Microbiol. 2013 Sep;36(6):376-82. doi: 10.1016/j.syapm.2013.04.002. Epub 2013 Jun 5.

Abstract

Members of the phylum Fibrobacteres are highly efficient cellulolytic bacteria, best known for their role in rumen function and as potential sources of novel enzymes for bioenergy applications. Despite being key members of ruminants and other digestive microbial communities, our knowledge of this phylum remains incomplete, as much of our understanding is focused on two recognized species, Fibrobacter succinogenes and F. intestinalis. As a result, we lack insights regarding the environmental niche, host range, and phylogenetic organization of this phylum. Here, we analyzed over 1000 16S rRNA Fibrobacteres sequences available from public databases to establish a phylogenetic framework for this phylum. We identify both species- and genus-level clades that are suggestive of previously unknown taxonomic relationships between Fibrobacteres in addition to their putative lifestyles as host-associated or free-living. Our results shed light on this poorly understood phylum and will be useful for elucidating the function, distribution, and diversity of these bacteria in their niches.

Keywords: Fibrobacter; Fibrobacteres; Host range; Phylogeny; Rumen.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cluster Analysis
  • Computational Biology
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Environmental Microbiology*
  • Fibrobacteres / classification*
  • Fibrobacteres / genetics*
  • Fibrobacteres / isolation & purification
  • Fibrobacteres / physiology
  • Genetic Variation*
  • Host Specificity
  • Phylogeny*
  • RNA, Ribosomal, 16S / genetics
  • Rumen / microbiology*
  • Ruminants
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S