Correlates of depressive symptoms among alcohol-using methadone maintained adults

Am J Addict. 2012 Nov;21 Suppl 1(0 1):S49-55. doi: 10.1111/j.1521-0391.2012.00300.x.

Abstract

Background: Alcohol-using clients are considered at great risk for hepatitis and ongoing liver damage. This study explores the correlates of depression among a sample of methadone maintained treatment (MMT) adults in the Los Angeles area, and is part of a larger study on hepatitis health promotion among MMT clients who use alcohol.

Objectives: We sought to determine correlates of depressive symptoms among moderate and heavy alcohol-using adults enrolled in methadone maintenance.

Methods: A cross-sectional correlation study was conducted of baseline data from a randomized control trial of adults (N= 189) receiving MMT in Los Angeles. Depressive symptoms were measured with the 10-item short-form CES-D.

Results: Multiple regression analysis revealed that pain and social support were key correlates of depressive symptoms. More pain was associated with higher levels of depressive symptoms (p= .001), while more social support was related to lower depressive symptom severity (p= .001). Having been in sufficiently poor health that a blood transfusion, clotting factors, or an organ transplant was necessary was associated with greater depressive symptomatology, as was having injected drugs in the past month (p= .024).

Conclusions: The findings from this investigation can aid clinicians in selecting clients to monitor for early signs of depression and encourage early treatment for opioid users with comorbidities.

Scientific significance: The use of an interdisciplinary team to care for MMT clients, routinely screen for depressive symptoms, and emphasize adequate pain control is indicated.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Alcohol Drinking / psychology*
  • Alcohol-Related Disorders / psychology*
  • Analgesics, Opioid / therapeutic use
  • Cross-Sectional Studies
  • Depression / psychology*
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Methadone / therapeutic use
  • Middle Aged
  • Multivariate Analysis
  • Opiate Substitution Treatment / psychology*
  • Opioid-Related Disorders / drug therapy
  • Opioid-Related Disorders / psychology*
  • Pain / psychology
  • Regression Analysis
  • Social Support
  • Substance Abuse, Intravenous / psychology

Substances

  • Analgesics, Opioid
  • Methadone