[Posterior reversible encephalopathy syndrome: 5 chemotherapy related cases]

Abstract

Posterior reversible encephalopathy syndrome, previously known as Reversible posterior leukoencephalopathy syndrome, is a clinical-radiological condition characterized by headache, altered mental functioning, seizures and visual alterations, with the magnetic resonance imaging showing cerebral edema, predominantly in the white matter with posterior distribution. Multiple clinical conditions can act as triggers. We present five oncology patients, four of them with acute lymphoblastic leukemia, receiving chemotherapy when they presented with this pathology. A prompt diagnosis, an appropriate therapy for hypertension, and a rapid control of the seizures are the keys to avoiding sequelae.

Keywords: Chemotherapy; Edema cerebral vasogénico; Hipertensión; Hypertension; Magnetic resonance imaging; Quimioterapia; Resonancia magnética; Reversible posterior leukoencephalopathy syndrome; Síndrome de leuconcefalopatía posterior reversible; Vasogenic cerebral edema.