Natural evolution from idiopathic photosensitive occipital lobe epilepsy to idiopathic generalized epilepsy in an untreated young patient

Brain Dev. 2014 Apr;36(4):346-50. doi: 10.1016/j.braindev.2013.06.002. Epub 2013 Jun 29.

Abstract

Idiopathic photosensitive occipital lobe epilepsy (IPOE) is an idiopathic localization-related epilepsy characterized by age-related onset, specific mode of precipitation, occipital photic-induced seizures--frequently consisting of visual symptoms--and good prognosis. This uncommon epilepsy, which usually starts in childhood or adolescence, has rarely been observed in families in which idiopathic generalized epilepsy also affects other members. We describe a nuclear family in which the proband showed electro-clinical features of idiopathic photosensitive occipital lobe epilepsy in childhood, which subsequently evolved into absences and a single generalized tonico-clonic seizure in early adolescence. His mother had features suggestive of juvenile myoclonic epilepsy. This case illustrates a continuum between focal and generalized entities in the spectrum of the so-called idiopathic (genetically determined) epileptic syndromes.

Keywords: Electroencephalography; Idiopathic photosensitive occipital lobe epilepsy; Juvenile myoclonic epilepsy; Photosensitivity.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Disease Progression
  • Electroencephalography
  • Epilepsy, Absence / physiopathology
  • Epilepsy, Generalized / physiopathology*
  • Epilepsy, Reflex / physiopathology*
  • Epilepsy, Tonic-Clonic / physiopathology
  • Family
  • Humans
  • Male
  • Occipital Lobe / physiopathology

Supplementary concepts

  • Epilepsy, Idiopathic Generalized