Abstract
Patients with chronic obstructive pulmonary disease (COPD) show a poor prognosis after myocardial infarction (MI) and percutaneous coronary intervention (PCI). We evaluated on-treatment platelet reactivity (PR) and several gene polymorphisms related to PR in 130 patients undergoing PCI with and without COPD. Those with concomitant COPD showed higher on-treatment PR values both at the time of PCI and 1 month after. This finding may contribute to explain the poor prognosis of COPD patients after MI and PCI.
Keywords:
COPD epidemiology.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Aged, 80 and over
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Comorbidity
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Female
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Humans
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Male
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Myocardial Infarction / drug therapy
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Myocardial Infarction / epidemiology*
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Myocardial Infarction / physiopathology
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Myocardial Infarction / therapy
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Percutaneous Coronary Intervention
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Platelet Activation / drug effects
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Platelet Activation / physiology*
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Platelet Aggregation Inhibitors / therapeutic use
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Prognosis
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Pulmonary Disease, Chronic Obstructive / epidemiology*
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Pulmonary Disease, Chronic Obstructive / physiopathology*
Substances
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Platelet Aggregation Inhibitors