Abstract
We report the observation of a necrotizing pneumonia due to methicillin-resistant Staphylococcus aureus harboring the Panton-Valentine leukocidin-encoding gene in a previously healthy neonate, with favorable clinical outcome in spite of extensive radiologic lesions. The case was linked to a cluster of 3 neonates colonized by Panton-Valentine leukocidin-producing, methicillin-resistant S. aureus through cross-transmission in the nursery, underlining the need to comply with standard infection control precautions in the maternity ward.
Copyright © 2013 S. Karger AG, Basel.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Bacterial Toxins / genetics
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Community-Acquired Infections / diagnosis
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Community-Acquired Infections / drug therapy
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Community-Acquired Infections / microbiology
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Community-Acquired Infections / transmission*
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Cross Infection / diagnosis
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Cross Infection / drug therapy
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Cross Infection / microbiology
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Cross Infection / transmission*
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Exotoxins / genetics
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Female
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Humans
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Infant, Newborn
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Infection Control / methods
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Leukocidins / genetics
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Methicillin Resistance*
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Methicillin-Resistant Staphylococcus aureus / genetics
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Methicillin-Resistant Staphylococcus aureus / isolation & purification*
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Methicillin-Resistant Staphylococcus aureus / pathogenicity
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Microbial Sensitivity Tests
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Nurseries, Hospital*
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Pneumonia, Staphylococcal / diagnosis
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Pneumonia, Staphylococcal / drug therapy
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Pneumonia, Staphylococcal / microbiology
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Pneumonia, Staphylococcal / transmission*
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Staphylococcal Infections / diagnosis
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Staphylococcal Infections / drug therapy
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Staphylococcal Infections / microbiology
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Staphylococcal Infections / transmission*
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Tomography, Spiral Computed
Substances
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Anti-Bacterial Agents
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin