Relationship between neutrophil to lymphocyte ratio and slow coronary flow

Clin Appl Thromb Hemost. 2015 Apr;21(3):251-4. doi: 10.1177/1076029613498814. Epub 2013 Jul 26.

Abstract

Objectives: We evaluated the relationship between neutrophil to lymphocyte ratio (NLR) and slow coronary flow (SCF).

Methods: A total of 180 participants were recruited to the present study. Of all the participants, 82 patients were with SCF and 98 participants were with normal coronary arteries. Basal characteristics were recorded. Coronary flow was quantified by thrombolysis in myocardial infarction frame count.

Results: Basal characteristics were similar between the 2 groups. The NLR was significantly higher in the SCF group when compared to the control group (2.3 ± 0.8 and 1.5 ± 0.4 respectively, P < .001). In multiple logistic regression analysis, NLR remained as the independent predictor of SCF (P < 0.001).

Conclusions: Our findings showed that NLR was significantly higher in the SCF group when compared to the control group with normal coronary arteries. We also showed that NLR was related to the presence of SCF rather than the extent of SCF. Besides these findings, we also showed the NLR as an independent predictor of SCF.

Keywords: atherosclerosis; cardiology; inflammation.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Coronary Circulation*
  • Coronary Vessels / physiopathology*
  • Female
  • Humans
  • Lymphocyte Count
  • Lymphocytes*
  • Male
  • Middle Aged
  • Neutrophils*
  • No-Reflow Phenomenon* / blood
  • No-Reflow Phenomenon* / physiopathology
  • No-Reflow Phenomenon* / therapy
  • Thrombolytic Therapy*