The atypical lipopolysaccharide of Francisella

Abstract

Bacterial lipopolysaccharides (LPSs) are ubiquitous molecules that are prominent components of the outer membranes of most gram-negative bacteria. Genetic and structural characterizations of Francisella LPS have revealed substantial differences when compared to more commonly studied LPSs of the Enterobacteriaceae. This review discusses both the general characteristics and the unusual features of Francisella LPS.

Keywords: 2,4-diacetamido-2,4,6-trideoxy-d-glucose; 2-acetamido-2,6-dideoxy-d-glucose; 2-acetamido-2-deoxy-d-galacturonamide; 3-deoxy-d-manno-octulosonic acid; 4,6-dideoxy-4-formamido-d-glucose; Francisella tularensis; GalNAcAN; Kdo; Kdo hydrolase; LPS; Lipid A; Lipopolysachharide; O-antigen; Qui2NAc4NAc; Qui4NFm; QuiNAc; Structure; lipopolysachharide.