Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface

Clin Ophthalmol. 2013:7:1623-33. doi: 10.2147/OPTH.S45122. Epub 2013 Aug 12.

Abstract

We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal-scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision.

Keywords: complex; full range; ocular surface; optical coherence tomography.