Two genomic species in Borrelia burgdorferi

Res Microbiol. 1990 May;141(4):465-75. doi: 10.1016/0923-2508(90)90072-x.

Abstract

A total of 13 Borrelia burgdorferi strains (responsible for Lyme borreliosis) and representatives of 3 other Borrelia species (B. hermsii, B. parkeri, B. turicatae) associated with relapsing fever were studied by DNA/DNA hybridization and rRNA gene-restriction patterns. Two genomic DNA hybridization groups were observed which could be differentiated by rRNA gene-restriction patterns. Moreover, the number and size of restriction fragments suggest the existence of a single set of 16 and 23 S rRNA genes in Borrelia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Borrelia burgdorferi Group / genetics*
  • Borrelia burgdorferi Group / isolation & purification
  • DNA, Bacterial* / analysis
  • Electrophoresis, Agar Gel
  • Genetics, Microbial
  • Humans
  • In Vitro Techniques
  • Lyme Disease / microbiology*
  • Nucleic Acid Hybridization*
  • Restriction Mapping

Substances

  • DNA, Bacterial