Outcome study of real-time MR-guided cervical periradicular injection therapy in an open 1.0 Tesla MRI system

Cardiovasc Intervent Radiol. 2014 Jun;37(3):756-62. doi: 10.1007/s00270-013-0738-4. Epub 2013 Sep 18.

Abstract

Purpose: To evaluate the accuracy, safety, and efficacy of cervical nerve root injection therapy using magnetic resonance guidance in an open 1.0 T MRI system.

Methods: Between September 2009 and April 2012, a total of 21 patients (9 men, 12 women; mean age 47.1 ± 11.1 years) underwent MR-guided cervical periradicular injection for cervical radicular pain in an open 1.0 T system. An interactive proton density-weighted turbo spin echo (PDw TSE) sequence was used for real-time guidance of the MR-compatible 20-gauge injection needle. Clinical outcome was evaluated on a verbal numeric rating scale (VNRS) before injection therapy (baseline) and at 1 week and 1, 3, and 6 months during follow-up.

Results: All procedures were technically successful and there were no major complications. The mean preinterventional VNRS score was 7.42 and exhibited a statistically significant decrease (P < 0.001) at all follow-up time points: 3.86 ± 1.53 at 1 week, 3.21 ± 2.19 at 1 month, 2.58 ± 2.54 at 3 months, and 2.76 ± 2.63 at 6 months. At 6 months, 14.3 % of the patients reported complete resolution of radicular pain and 38.1 % each had either significant (4-8 VNRS score points) or mild (1-3 VNRS score points) relief of pain; 9.5 % experienced no pain relief.

Conclusion: Magnetic resonance fluoroscopy-guided periradicular cervical spine injection is an accurate, safe, and efficacious treatment option for patients with cervical radicular pain. The technique may be a promising alternative to fluoroscopy- or CT-guided injections of the cervical spine, especially in young patients and in patients requiring repeat injections.

MeSH terms

  • Adult
  • Aged
  • Analgesics / administration & dosage*
  • Anesthetics / administration & dosage*
  • Female
  • Humans
  • Injections, Intra-Articular
  • Magnetic Resonance Imaging, Interventional / instrumentation*
  • Male
  • Middle Aged
  • Neck Pain / drug therapy*
  • Pain Measurement
  • Prospective Studies
  • Radiculopathy / drug therapy*
  • Treatment Outcome

Substances

  • Analgesics
  • Anesthetics