Influence of patient, physician, and hospital factors on 30-day readmission following pancreatoduodenectomy in the United States

JAMA Surg. 2013 Dec;148(12):1095-102. doi: 10.1001/jamasurg.2013.2509.

Abstract

IMPORTANCE It is not known whether hospital and surgeon volumes have an association with readmission among patients undergoing pancreatoduodenectomy.

Objective: To evaluate patient-, surgeon-, and hospital-level factors associated with readmission.

Design, setting, and participants: Retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER)-Medicare data with cases diagnosed from January 1, 1998, to December 31, 2005, and followed up until December 2007. Population-based cancer registry data were linked to Medicare data for the corresponding patients. A total of 1488 unique individuals who underwent a pancreatoduodenectomy were identified.

Interventions: Undergoing pancreatoduodenectomy at hospitals classified by volume of pancreatoduodenectomy procedures performed at the facility were either very-low, low, medium, or high volume. Undergoing pancreatoduodenectomy by surgeons classified by volume of pancreatoduodenectomy procedures performed by the surgeon were either very-low, low, medium, or high volume.

Main outcomes and measures: In-hospital morbidity, mortality, and 30-day readmission were examined.

Results: The median age was 74 years, and 1436 patients (96.5%) had a least 1 medical comorbidity. Patients were treated by 575 distinct surgeons at 298 distinct hospitals. Length of stay was longest (median, 17 days) and 90-day mortality highest (17.2%) at very-low-volume hospitals (P < .001). Among all pancreatoduodenectomy patients, 292 (21.3%) were readmitted within 30 days of discharge. There was no effect of surgeon volume and a modest effect of hospital volume (odds ratio for highest- vs lowest-volume quartiles, 1.85; 95% CI, 1.22-2.80; P = .02). The presence of significant preoperative medical comorbidities was associated with an increased risk for hospital readmission after pancreatoduodenectomy. A comorbidity score greater than 13 had a pronounced effect on the chance of readmission following pancreatoduodenectomy (odds ratio, 2.06; 95% CI, 1.56-2.71; P < .001). The source of variation in readmission was primarily attributable to patient-related factors (95.4%), while hospital factors accounted for 4.3% of the variability and physician factors for only 0.3%.

Conclusions and relevance: Nearly 1 in 5 patients are readmitted following pancreatoduodenectomy. While variation in readmission is, in part, attributable to differences among hospitals, the largest share of variation was found at the patient level.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Attitude of Health Personnel
  • Cohort Studies
  • Comorbidity*
  • Cross Infection / epidemiology
  • Female
  • Health Care Surveys
  • Hospital Mortality
  • Humans
  • Length of Stay
  • Male
  • Medicare / statistics & numerical data
  • Outcome Assessment, Health Care
  • Pancreatic Neoplasms / mortality
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / surgery*
  • Pancreaticoduodenectomy / adverse effects*
  • Pancreaticoduodenectomy / methods
  • Pancreaticoduodenectomy / mortality
  • Patient Readmission / statistics & numerical data*
  • Postoperative Complications / mortality
  • Postoperative Complications / physiopathology
  • Practice Patterns, Physicians'
  • Retrospective Studies
  • Risk Factors
  • SEER Program
  • Survival Rate
  • Time Factors
  • United States
  • Workload*