Drug repositioning from bench to bedside: tumour remission by the antihelmintic drug mebendazole in refractory metastatic colon cancer

Acta Oncol. 2014 Mar;53(3):427-8. doi: 10.3109/0284186X.2013.844359. Epub 2013 Oct 28.

Authors

Peter Nygren¹, Rolf Larsson

Affiliation

¹ Department of Radiology, Oncology and Radiation Science, Section of Oncology, Uppsala University , Uppsala , Sweden.

PMID: 24160353
DOI: 10.3109/0284186X.2013.844359

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Antineoplastic Agents / therapeutic use*
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Colonic Neoplasms / drug therapy*
Colonic Neoplasms / pathology*
Drug Repositioning*
Humans
Liver / drug effects
Liver / enzymology
Male
Mebendazole / pharmacology
Mebendazole / therapeutic use*

Substances

Antineoplastic Agents
Mebendazole