Unfolding the mystery of olfactory receptor gene expression

Yun Rose Li; Hiroaki Matsunami

doi:10.1016/j.devcel.2013.10.012

Unfolding the mystery of olfactory receptor gene expression

Dev Cell. 2013 Oct 28;27(2):128-129. doi: 10.1016/j.devcel.2013.10.012.

Authors

Yun Rose Li¹, Hiroaki Matsunami²

Affiliations

¹ Medical Scientist Training Program and Genetics and Gene Regulation Graduate Program, Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
² Department of Molecular Genetics and Microbiology, Department of Neurobiology, Duke Institute for Brain Sciences, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: hiroaki.matsunami@duke.edu.

Abstract

Reporting recently in Cell, Dalton et al. (2013) identify a central role for the unfolded protein response in the regulation of olfactory receptor expression, unveiling molecular players in an elaborate feedback loop that controls the stabilization and establishment of single olfactory receptor gene choice.

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Animals
Bile Ducts, Intrahepatic / surgery*
Cholelithiasis / surgery*
Gallstones / surgery*
Humans
Laser Therapy*
Male

Abstract

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