Comparison of endoscopic retrograde cholangiopancreatography between elderly and younger patients for common bile duct stones

Clin Ter. 2013;164(5):e353-8. doi: 10.7417/CT.2013.1612.

Abstract

Background: Choledocholithiasis is increasing in elderly subjects. The introduction of endoscopic retrograde cholangiopancreatography with biliary sphincterotomy has almost replaced surgery in the treatment of this condition. The aim of the present study was to evaluate the rates of successful clearance of common bile duct stones and the endoscopic techniques used in a population aged 75 years or older compared with those in a younger age group.

Materials and methods: A retrospective analysis was made of data related patients who underwent endoscopic retrograde cholangiopancreatography for choledocolithiasis in the period 2010-2011. For all patients, factors such as sex, age at diagnosis, endoscopic treatment (stone extraction using baskets and balloon, mechanical lithotripsy and balloon dilatation of the ampulla, placement of a stent or a naso-biliary tube) and need of surgery were analysed. Two groups of patients were identified: patients aged <75 years (Group A) and patients aged ≥75 years (Group B). For the statistical analysis Mann-Whitney test and Fischer's Exact test were used.

Results: A total of 234 patients were enrolled in the study (94 in Group A, 140 in Group B). No statistically significant differences were observed as far concerns sex, previous cholecystectomy, gallbladder stones and periampullary diverticula, but only for common bile duct dilatation. Complete clearance of common bile duct stones was achieved in 230 patients (97.5%).

Conclusions: The present data are in keeping with those presented in the literature, which confirm that endoscopic retrograde cholangiopancreatography is a safe and effective procedure also in older patients.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age of Onset
  • Aged
  • Aged, 80 and over
  • Cholangiopancreatography, Endoscopic Retrograde* / adverse effects
  • Cholangitis / epidemiology
  • Cholecystectomy / statistics & numerical data
  • Cholelithiasis / epidemiology
  • Comorbidity
  • Duodenoscopy
  • Equipment Design
  • Female
  • Fluoroscopy
  • Gallstones / diagnostic imaging*
  • Gallstones / epidemiology
  • Gallstones / surgery
  • Humans
  • Intubation
  • Lithotripsy
  • Male
  • Middle Aged
  • Radiography, Interventional
  • Retrospective Studies
  • Sphincterotomy, Endoscopic
  • Sphincterotomy, Transduodenal
  • Stents
  • Treatment Outcome