Sinus node dysfunction in adult systemic lupus erythematosus flare: A case report

Mod Rheumatol. 2015 May;25(3):472-5. doi: 10.3109/14397595.2013.843744. Epub 2013 Oct 21.

Abstract

Cardiac involvement can affect up to 50% of the systemic lupus erythematosus (SLE) patients but conduction system disturbances in SLE are less commonly described. For an early detection of this complication in the acute phase of SLE a whole cardiovascular examination and periodic electrocardiographic monitoring are recommended. We describe a patient who was diagnosed with flare up of lupus activity manifesting as sinus node dysfunction presenting as profound sinus bradycardia. She was successfully treated with high-dose methylprednisolone therapy.

Keywords: Methylprednisolone; Sinus bradycardia; Systemic lupus erythematosus.

Publication types

  • Case Reports

MeSH terms

  • Bradycardia / drug therapy
  • Bradycardia / etiology*
  • Bradycardia / physiopathology
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / drug therapy
  • Lupus Erythematosus, Systemic / physiopathology
  • Methylprednisolone / therapeutic use
  • Sick Sinus Syndrome / drug therapy
  • Sick Sinus Syndrome / etiology*
  • Sick Sinus Syndrome / physiopathology
  • Treatment Outcome
  • Young Adult

Substances

  • Glucocorticoids
  • Methylprednisolone