Beyond liver fibrosis: hepatic stellate cell senescence links obesity to liver cancer by way of the microbiome

Hepatology. 2014 Jun;59(6):2413-5. doi: 10.1002/hep.26932. Epub 2014 Apr 9.

Authors

Nicholas A Shackel¹, Mathew A Vadas, Jennifer R Gamble, Geoffrey W McCaughan

Affiliation

¹ Liver Injury and Cancer Group, Centenary Institute, Sydney, NSW, Australia; A.W. Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

PMID: 24273014
DOI: 10.1002/hep.26932

No abstract available

Publication types

Comment

MeSH terms

Animals
Cellular Senescence*
Deoxycholic Acid / metabolism*
Gastrointestinal Tract / metabolism*
Gastrointestinal Tract / microbiology*
Hepatic Stellate Cells / metabolism*
Humans
Liver Neoplasms / metabolism*
Male
Obesity / metabolism*

Substances

Deoxycholic Acid