Chemotherapy and immunotherapy of brain tumors: what the epileptologist must know

Abstract

I present an overview of therapy for the most common brain tumors encountered in clinical practice if adult patients. Current therapy paradigms and evolving therapies are reviewed. The introduction of non-enzyme-inducing antiepileptic drugs (NEIADs) has simplified the approach to combined medical treatment of epilepsy and brain tumors, but the major interactions between enzyme-inducing antiepileptic drugs (EIAEDs) are included, to serve as guidance in selecting these medications if they are required.

Keywords: Bevacizumab; CNS neoplasm; Glioma; O6-methylguanine DNA methyltransferase; Temozolomide.