Energy balance and metabolism after cancer treatment

Semin Oncol. 2013 Dec;40(6):745-56. doi: 10.1053/j.seminoncol.2013.09.011.

Abstract

Unfavorable physiological, biological, and behavioral alterations during and following treatment for cancer may lead to chronic energy imbalance predisposing to a myriad of deleterious health conditions including obesity, dyslipidemia, and the metabolic syndrome. In addition to the cardiovascular and musculoskeletal effects of these conditions, energy imbalance and metabolic changes after cancer treatment can also affect cancer-related morbidity and mortality. To this end, lifestyle interventions such as diet and physical activity are especially relevant to mitigate the deleterious impact of chronic energy imbalance in cancer survivors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antineoplastic Agents / adverse effects
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / prevention & control
  • Diet
  • Dyslipidemias / etiology*
  • Dyslipidemias / prevention & control
  • Energy Metabolism* / drug effects
  • Energy Metabolism* / radiation effects
  • Exercise
  • Humans
  • Life Style
  • Metabolic Syndrome / etiology*
  • Metabolic Syndrome / prevention & control
  • Neoplasms / therapy*
  • Obesity / etiology*
  • Obesity / prevention & control
  • Radiotherapy / adverse effects
  • Risk Factors
  • Stem Cell Transplantation / adverse effects

Substances

  • Antineoplastic Agents