Gold catalysed synthesis of 3-alkoxyfurans at room temperature

Chem Commun (Camb). 2014 Feb 9;50(11):1302-4. doi: 10.1039/c3cc48290a.

Abstract

Synthetically important 3-alkoxyfurans can be prepared efficiently via treatment of acetal-containing propargylic alcohols (obtained from the addition of 3,3-diethoxypropyne to aldehydes) with 2 mol% gold catalyst in an alcohol solvent at room temperature. The resulting furans show useful reactivity in a variety of subsequent transformations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry
  • Catalysis
  • Furans / chemical synthesis*
  • Gold / chemistry*
  • Propanols / chemistry
  • Temperature

Substances

  • Alkynes
  • Furans
  • Propanols
  • Gold
  • propargyl alcohol