Ultrasound-mediated drug delivery is a promising means of enhancing delivery, distribution and effectiveness of drugs within tumours. In this review, prospects for exploiting ultrasound to improve the tumour delivery and distribution of radiolabelled antibodies for radioimmunotherapy and to overcome barriers imposed by tumour microenvironment are discussed.
Keywords: cancer; drug delivery; monoclonal antibodies; radioimmunotherapy; ultrasound.
Copyright © 2013 John Wiley & Sons, Ltd.