[Pancreatic cancer showing complete pathological response to preoperative chemoradiotherapy-a case report]

Gan To Kagaku Ryoho. 2013 Nov;40(12):1872-4.
[Article in Japanese]

Abstract

The patient was a 57-year-old man who was diagnosed as having stage IVa pancreatic cancer. We selected preoperative chemoradiation therapy( gemcitabine[ GEM] plus S-1; and radiation therapy[ RT], 50.4 Gy/28 Fr). A month later, distal pancreatectomy was performed after completion of the course of chemoradiation therapy. Histopathological examination revealed no cancer cells in the pancreas or the dissected lymph nodes. The pathological effect was judged as grade IV. The patient has had no recurrence for 8 months since pancreatectomy.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Chemoradiotherapy*
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives
  • Drug Combinations
  • Gemcitabine
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Oxonic Acid / administration & dosage
  • Pancreatectomy
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / therapy*
  • Tegafur / administration & dosage
  • Treatment Outcome

Substances

  • Drug Combinations
  • Deoxycytidine
  • S 1 (combination)
  • Tegafur
  • Oxonic Acid
  • Gemcitabine