The glomic artery supply of carotid body tumors and implications for embolization

J Clin Neurosci. 2014 Jul;21(7):1176-9. doi: 10.1016/j.jocn.2013.11.012. Epub 2013 Dec 12.

Abstract

Carotid body tumors (CBT) are rare neuroendocrine neoplasms that usually present in the third or fourth decades of life and are benign in more than 95% of cases. In the angiographic literature, the arterial supply to carotid body tumors is well documented but is often incomplete, with infrequent mention of the glomic artery, a common arterial feeder described in the anatomic and pathologic literature. Through a review of our neuroendovascular patient database, we identified eight patients with CBT undergoing transarterial embolization followed by resection. Mean patient age was 51.5 years (range 29-82), and all patients were female. Mean tumor size was 91.2 cc (standard deviation [SD] 61.1, median 67.7 cc). After embolization, greater than 90% flow reduction was achieved in 5/8 patients (63%); 60-80% flow reduction was achieved in the remaining patients. Mean operative blood loss was 166 cc (SD 100, median 122 cc) and mean operative time was 252 minutes (SD 134.5, median 155 minutes). Pre-embolization angiography was reviewed to identify a glomic artery, defined as a dominant artery supplying the CBT arising from the region of the carotid bifurcation. In six of eight patients (75%) a glomic artery could be identified, arising from the common carotid artery in 4/6 patients and the external carotid artery in 2/6 patients. Thus, glomic artery to supply to CBT was identified in the majority of patients in this series. Knowledge of its presence and identification as a direct supplier, frequently from the common carotid artery itself, provides an avenue for more thorough preoperative embolization of CBT.

Keywords: Carotid body; Embolization; Endovascular; Glomic; Onyx.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography
  • Blood Loss, Surgical
  • Carotid Artery, Common / pathology
  • Carotid Body Tumor / surgery*
  • Embolization, Therapeutic / methods*
  • Endovascular Procedures / methods*
  • Female
  • Humans
  • Imaging, Three-Dimensional
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome