Pharmacologic targets and peritoneal membrane remodeling

Perit Dial Int. 2014 Jan-Feb;34(1):114-23. doi: 10.3747/pdi.2011.00332.

Abstract

Peritoneal dialysis (PD) is associated with functional and structural changes of the peritoneal membrane, also known as peritoneal remodeling. The peritoneal membrane is affected by many endogenous and exogenous factors such as cytokines, PD fluids, and therapeutic interventions. Here, we present an overview of various studies that have investigated pharmacologic interventions aimed at regression of peritoneal damage and prolongation of PD treatment.

Keywords: Therapeutic interventions.

Publication types

  • Review

MeSH terms

  • Humans
  • Neovascularization, Pathologic / prevention & control
  • Peritoneal Dialysis / adverse effects*
  • Peritoneal Fibrosis / etiology
  • Peritoneal Fibrosis / prevention & control
  • Peritoneum / drug effects*
  • Peritoneum / pathology*
  • Peritonitis / etiology
  • Peritonitis / prevention & control