Improved methodologies for the study of adipose biology: insights gained and opportunities ahead

J Lipid Res. 2014 Apr;55(4):605-24. doi: 10.1194/jlr.R046441. Epub 2014 Feb 16.

Abstract

Adipocyte differentiation and function have become areas of intense focus in the field of energy metabolism; however, understanding the role of specific genes in the establishment and maintenance of fat cell function can be challenging and complex. In this review, we offer practical guidelines for the study of adipocyte development and function. We discuss improved cellular and genetic systems for the study of adipose biology and highlight recent insights gained from these new approaches.

Keywords: adipogenesis; energy metabolism; obesity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adipocytes / physiology
  • Adipogenesis
  • Adipose Tissue / cytology
  • Adipose Tissue / physiology*
  • Animals
  • Cell Culture Techniques
  • Cell Lineage
  • Cell Tracking
  • Energy Metabolism
  • Gene Expression
  • Humans
  • Lipid Metabolism
  • Models, Animal
  • Organ Specificity