An imbalance between protective and detrimental molecular pathways is associated with right ventricular dysfunction in congenital heart diseases with outflow obstruction

Int J Cardiol. 2014 Apr 1;172(3):e519-21. doi: 10.1016/j.ijcard.2014.01.077. Epub 2014 Jan 24.
No abstract available

Keywords: Congenital heart disease; Right ventricle failure; Right ventricle outflow obstruction.

Publication types

  • Letter

MeSH terms

  • Echocardiography
  • Follow-Up Studies
  • G-Protein-Coupled Receptor Kinase 2 / metabolism*
  • Heart Atria / metabolism
  • Heart Atria / pathology
  • Heart Atria / physiopathology
  • Heart Defects, Congenital / complications*
  • Heart Defects, Congenital / diagnosis
  • Heart Defects, Congenital / surgery
  • Humans
  • Myocytes, Cardiac / metabolism*
  • Myocytes, Cardiac / pathology
  • Phosphorylation
  • Receptors, Adrenergic, beta / metabolism*
  • Ventricular Dysfunction, Right / etiology
  • Ventricular Dysfunction, Right / metabolism*
  • Ventricular Dysfunction, Right / physiopathology
  • Ventricular Function, Right / physiology*
  • Ventricular Outflow Obstruction / etiology
  • Ventricular Outflow Obstruction / metabolism*
  • Ventricular Outflow Obstruction / physiopathology

Substances

  • Receptors, Adrenergic, beta
  • G-Protein-Coupled Receptor Kinase 2