Probable longer incubation period for human infection with avian influenza A(H7N9) virus in Jiangsu Province, China, 2013

Epidemiol Infect. 2014 Dec;142(12):2647-53. doi: 10.1017/S0950268814000272. Epub 2014 Feb 24.

Abstract

Human infection with the emerging avian influenza A(H7N9) virus in China in 2013 has raised global concerns. We conducted a retrospective descriptive study of 27 confirmed human influenza A(H7N9) cases in Jiangsu Province, to elaborate poultry-related exposures and to provide a more precise estimate of the incubation periods of the illness. The median incubation period was 6 days (range 2-10 days) in cases with single known exposure and was 7·5 days (range 6·5-12·5 days) in cases with exposures on multiple days, difference between the two groups was not significant (Z = -1·895, P = 0·058). The overall median incubation period for all patients was estimated to be 7·5 days (range 2-12·5 days). Our findings further highlight the necessity for public health authorities to extend the period of medical surveillance from 7 days to 10 days.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • China / epidemiology
  • Communicable Diseases, Emerging / transmission*
  • Communicable Diseases, Emerging / virology
  • Demography
  • Disease Outbreaks*
  • Female
  • Humans
  • Influenza A Virus, H7N9 Subtype*
  • Influenza in Birds / transmission*
  • Influenza in Birds / virology
  • Influenza, Human / epidemiology*
  • Influenza, Human / virology
  • Male
  • Middle Aged
  • Poultry
  • Real-Time Polymerase Chain Reaction
  • Retrospective Studies
  • Zoonoses