Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated Bacterium Actinokineospora sp. Strain EG49

Janno Harjes; Taewoo Ryu; Usama Ramadan Abdelmohsen; Lucas Moitinho-Silva; Hannes Horn; Timothy Ravasi; Ute Hentschel

doi:10.1128/genomeA.00160-14

Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated Bacterium Actinokineospora sp. Strain EG49

Genome Announc. 2014 Mar 6;2(2):e00160-14. doi: 10.1128/genomeA.00160-14.

Authors

Janno Harjes¹, Taewoo Ryu, Usama Ramadan Abdelmohsen, Lucas Moitinho-Silva, Hannes Horn, Timothy Ravasi, Ute Hentschel

Affiliation

¹ Department of Botany II, Julius-von-Sachs Institute for Biological Sciences, University of Würzburg, Würzburg, Germany.

Abstract

The marine sponge-associated bacterium Actinokineospora sp. strain EG49 produces the antitrypanosomal angucycline-like compound actinosporin A. The draft genome of Actinokineospora sp. EG49 has a size of 7.5 megabases and a GC content of 72.8% and contains 6,629 protein-coding sequences (CDS). antiSMASH predicted 996 genes residing in 36 secondary metabolite gene clusters.