57Co-bleomycin scintigraphy for the staging of lung cancer

Cancer. 1989 Mar 15;63(6):1119-22. doi: 10.1002/1097-0142(19890315)63:6<1119::aid-cncr2820630613>3.0.co;2-x.

Abstract

The value of Cobalt-57 bleomycin (57Co-BLM) scintigraphy in the detection of lymph node metastases in the hilum and mediastinum was investigated in 132 patients with peripherally located lung cancer. In one half of the patients with metastases, these were visualized. Specificity was 98%. These results were better than those obtained with chest radiography and conventional roentgen tomography. 57Co-BLM scintigraphy is routinely used in the staging of patients with lung cancer, obviating the need for mediastinoscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bleomycin*
  • Cobalt Radioisotopes*
  • False Negative Reactions
  • Female
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lymphatic Metastasis
  • Male
  • Mediastinal Neoplasms / diagnostic imaging
  • Mediastinal Neoplasms / secondary
  • Middle Aged
  • Neoplasm Staging
  • Radionuclide Imaging
  • Tomography, X-Ray Computed

Substances

  • Cobalt Radioisotopes
  • Bleomycin