Abstract
In January to February 2014, 16 hand, foot and mouth disease (HFMD) cases were identified in Edinburgh, United Kingdom. All presented with atypical features, with most (n=13) resembling eczema herpeticum or chickenpox. Coxsackievirus A6 (CV-A6) was identified in all the typed cases (n=11). As atypical forms of HFMD associated with CV-A6 are likely to emerge throughout Europe, clinicians should be alert to unusual clinical presentations of HFMD and virologists aware of effective diagnostic testing and enterovirus typing methods.
MeSH terms
-
Adult
-
Chickenpox / etiology
-
Child, Preschool
-
Coxsackievirus Infections / complications*
-
Coxsackievirus Infections / epidemiology
-
Coxsackievirus Infections / virology
-
Diagnosis, Differential
-
Disease Outbreaks
-
Enterovirus A, Human / genetics*
-
Enterovirus A, Human / isolation & purification
-
Female
-
Hand, Foot and Mouth Disease / complications*
-
Hand, Foot and Mouth Disease / epidemiology
-
Hand, Foot and Mouth Disease / virology*
-
Humans
-
Infant
-
Kaposi Varicelliform Eruption / etiology
-
Male
-
Middle Aged
-
RNA, Viral / genetics
-
Real-Time Polymerase Chain Reaction
-
Retrospective Studies
-
Sentinel Surveillance
-
Sequence Analysis, DNA
-
United Kingdom / epidemiology