Antibacterial activity of Ag-Au alloy NPs and chemical sensor property of Au NPs synthesized by dextran

Kalipada Bankura; Dipanwita Maity; Md Masud Rahaman Mollick; Dibyendu Mondal; Biplab Bhowmick; Indranil Roy; Tarapada Midya; Joy Sarkar; Dipak Rana; Krishnendu Acharya; Dipankar Chattopadhyay

doi:10.1016/j.carbpol.2014.02.047

Antibacterial activity of Ag-Au alloy NPs and chemical sensor property of Au NPs synthesized by dextran

Carbohydr Polym. 2014 Jul 17:107:151-7. doi: 10.1016/j.carbpol.2014.02.047. Epub 2014 Feb 22.

Affiliations

¹ Department of Polymer Science and Technology, University College of Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700 009, India; Department of Chemistry, Tamralipta Mahavidyalaya, Tamluk, Purba Medinipur 721636, India.
² Department of Polymer Science and Technology, University College of Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700 009, India.
³ Department of Botany, Molecular and Applied Mycology and Plant Pathology Laboratory, University of Calcutta, Kolkata 700 019, India.
⁴ Department of Chemical and Biological Engineering, Industrial Membrane Research Institute, University of Ottawa, 161 Louis Pasteur St., Ottawa, ON K1N 6N5, Canada.
⁵ Department of Polymer Science and Technology, University College of Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700 009, India. Electronic address: dipankar.chattopadhyay@gmail.com.

PMID: 24702930
DOI: 10.1016/j.carbpol.2014.02.047

Abstract

Gold and silver-gold alloy nanoparticles with mean diameter of 10nm and narrow size distribution were prepared by reduction of the correspondent metal precursors using aqueous dextran solution which acts as both a reducing and capping agent. The formation of nanoparticles was characterized by UV-vis spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD) and dynamic light scattering (DLS). The silver and gold nanoparticles exhibited absorption maxima at 425 and 551 nm respectively; while for the bimetallic Ag-Au alloy appeared 520 nm in between them. TEM images showed monodispersed particles in the range of 8-10nm. The crystallinity of the nanoparticles was assured by XRD analysis. DLS data gave particle size distribution. The dextran stabilized Au nanoparticles used as a colorimetric sensor for detection and estimation of pesticide present in water. The dextran stabilized Ag-Au alloy nanoparticles exhibited interesting antimicrobial activity against bacteria at micromolar concentrations.

Keywords: Ag–Au alloy; Antimicrobial activity; Colorimetric sensor; Dextran stabilized nanoparticles; Nanoparticles.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alloys / chemistry*
Alloys / pharmacology*
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology
Bacteria / drug effects
Chemistry Techniques, Analytical / instrumentation*
Dextrans / chemistry*
Drug Stability
Gold / chemistry*
Metal Nanoparticles / chemistry*
Particle Size
Pesticides / analysis
Pesticides / chemistry
Silver / chemistry*
Water / chemistry

Substances

Alloys
Anti-Bacterial Agents
Dextrans
Pesticides
Water
Silver
Gold